Guardian Science Weekly

Menopause: could a new brain-based treatment cure hot flushes?

Loading player...
A first-of-its-kind non-hormonal drug to treat hot flushes has been approved in the US. Targeting connections in the brain that change during menopause, the drug, called fezolinetant, could provide relief for those who aren’t able to take hormonal replacement therapy. Madeleine Finlay speaks to endocrinologist and menopause specialist Prof Annice Mukherjee to find out what we know about the mechanism that causes hot flushes, how this new drug works, and what it might mean for those experiencing menopause in the future.. Help support our independent journalism at theguardian.com/sciencepod
18 May 2023 English United Kingdom Science · Nature

Other recent episodes

Can degrowth save the climate?

Since the 1960s, global GDP has been rapidly rising and living standards have reached record highs. But something else has been rocketing up too – carbon emissions. For years, scientists and economists have been asking: is it possible to grow without heating and polluting the Earth? And as the climate…
26 Feb 18 min

The truth about fat, and its complex role in our health

For a long time fat was seen simply as an inert yellow substance wrapping around our bodies, but now that’s changing. Scientists are beginning to understand that our fat is actually intricate and dynamic, constantly in conversation with the rest of the body. It’s now even considered by some to…
24 Feb 16 min

Psychedelics for depression, dart frog poison and why do we have chins?

Madeleine Finlay sits down with science editor Ian Sample and science correspondent Nicola Davis to discuss three eye-catching stories, including the impact of a powerful psychedelic on depression, answers on the death of Russian opposition leader Alexei Navalny, and an explanation to the mystery of why humans have chins. Help…
19 Feb 19 min

Should we really all be taking magnesium supplements?

Testimonials about the beneficial health effects of magnesium supplements abound online, with influencers claiming that a daily pill can help with everything from anxiety to sleep and brain fog. But do any of these claims stack up? Ian Sample is joined by co-host Madeleine Finlay to find out where the…
17 Feb 16 min

What bots talk about when they think humans aren’t listening

In late January a new social media site took a certain corner of the internet by storm. Moltbook was conceived as a space where AI assistants could let off steam, chat and compare notes on their bosses, but it quickly became the focus of breathless claims that the singularity had…
12 Feb 16 min
All episodes